Click the picture to zoom in.
Burkitt’s Lymphoma is a lymphoma seen in adolescents and can present as a jaw
lesion though it can also occur in the abdomen. It is caused by t(8;14)
aka a translocation of c-myc and heavy chain IgG. On histology
slides it has a starry sky appearance. It is associated with EBV
infection.
So what’s this silly
picture have to do with any of that? Well I’m glad you asked.
Mickey Mouse represents the c-myc (get it Mickey Mouse, C-MYC haha…).
The 8 stars represent chromosome #8 where c-myc is normally found. And
Van Gogh’s "Starry Night" represents the starry sky appearance
that’s supposedly seen under the microscope (personally I don’t see it, but
consider it a buzzword).
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